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Scientists can have fun and adventure. Dr. Springer's lecture will provide four insights into how. Making discoveries: How do the white cells in our blood recognize other cells or exit the bloodstream to fight cancer or infection? The discovery of adhesion molecules, including integrins, using antibodies unveiled the answer. Unraveling mechanisms: How do integrins transduce chemical signals into cell locomotion and other vital cell functions? The mechanisms hinge on integrins adopting three "conformational states" and transmitting forces across cell membranes between extracellular footholds and the cytoskeleton, thereby stabilizing integrins' active state. Engaging in entrepreneurship: New targets in cell-cell recognition and trafficking and new molecular mechanisms have enabled the development of new therapeutics and the launch of companies to develop and provide them to patients. Here lies the origin of biomedical success stories including, LeukoSite, Morphic Therapeutic, and the Institute for Protein Innovation. Learning how to learn: Scientists are privileged because their domain requires them to perpetually learn and develop new skills, ideas, and even disciplines. Research shows that those who challenge themselves and deliberately practice new skills succeed more than those who possess a high IQ. Timothy Springer is an award-winning scientist, eight-time entrepreneur, and philanthropist. He is currently Latham Family Professor of Biological Chemistry and Molecular Pharmacology and Professor of Medicine at Harvard Medical School and Boston Children's Hospital. Dr. Springer has more than 500 publications and 30 patents. He is a member of the National Academy of Sciences and was awarded the Cancer Research Institute Coley Award, the Crafoord Prize, and the prestigious Canada International Gairdner Prize among others. After earning his Ph.D. in molecular biology and biochemistry from Harvard, Dr. Springer began his post-graduate career in the laboratory of N
  • Start:June 25, 2021 Time: 8:00 PM
  • End:June 25, 2021 Time: 9:00 PM
  • Recurring
  • Where:The Cornelia Clapp Auditorium, Marine Biological Laboratory, 7 MBL Street, Not found, Not found, Not found, 02540
  • Phone:N/A
  • Event Type: Other
  • Ticket Price:N/A
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